Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL1537449 | 1.00 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL18694957 | 1.00 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL3653477 | 1.00 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL1537443 | 1.00 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL7722171 | 0.94 | SLC7A5 (0.54) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL16401105 | 0.93 | SLC1A1 (0.39) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL8886412 | 0.93 | SLC1A1 (0.39) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL22664570 | 0.93 | SLC1A1 (0.39) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Leucine SCHEMBL27481735 | 0.91 | SLC7A5 (0.60) | SLC1A1SLC1A3SLC1A2SLC7A5DPP4 | |
| Isoleucine SCHEMBL27304644 | 0.90 | SLC1A1 (0.41) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014194809-A1 | NEW COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING, AND SYNTHESIS, NANO-STRUCTURE AND USE THEREOF | 永光制药有限公司 (CN) | 2014-12-11 | — | — | WO | disclosed |