Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL27481734 | 0.94 | SLC1A1 (0.37) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL3194053 | 0.93 | SLC1A3 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL3194059 | 0.93 | SLC1A3 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL4416801 | 0.93 | SLC1A3 (0.46) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL23531113 | 0.92 | SLC1A3 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL23531111 | 0.92 | SLC1A3 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL5970331 | 0.90 | SLC1A3 (0.43) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL16401005 | 0.90 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL1537449 | 0.90 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Isoleucine SCHEMBL3653477 | 0.90 | SLC1A1 (0.44) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069346-C | Expression and secretion of hereologous proteins by yarrowia lipolytica transformants | PFIZER (US) | 2001-08-08 | — | — | CN | disclosed |
| CN-1034428-C | Expression and Secretion of Heterologous Proteins Using Yarrowia lipolytica Transformants | PFIZER (US) | 1997-04-02 | — | — | CN | disclosed |
| CN-1141339-A | Expression and secretion of hereologous proteins by yarrowia lipolytica transformants | PFIZER (US) | 1997-01-29 | — | — | CN | disclosed |
| CN-1138632-A | Expression and secretion of hereologous proteins by yarrowia lipolytica transformants | PFIZER (US) | 1996-12-25 | — | — | CN | disclosed |
| CN-86106522-A | Expression and Secretion of Heterologous Proteins Using Yarrowia lipolytica Transformants | — | 1987-09-16 | — | — | CN | disclosed |