Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMURF2 | Q9HAU4 | 3/20 | 0.35 |
| ▸ | SMURF1 | Q9HCE7 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401340 | 0.93 | NPC1 (0.39) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL19315732 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16401052 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16401050 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16409697 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16400289 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16401342 | 0.77 | LMNA (0.42) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16401341 | 0.77 | LMNA (0.42) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16400155 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16401266 | 0.74 | SMURF2 (0.40) | MAPTSMURF2SMURF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022185-B1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2017-09-06 | — | — | EP | claimed |
| US-9497970-B2 | Pesticide compounds | BASF SE (DE) | 2016-11-22 | — | — | US | claimed |
| US-20160157491-A1 | Pesticide Compounds | BASF SE (DE) | 2016-06-09 | — | — | US | claimed |
| EP-3022185-A1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2016-05-25 | — | — | EP | claimed |
| WO-2015007682-A1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2015-01-22 | — | — | WO | claimed |
| EP-3022185-B1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-9497970-B2 | Pesticide compounds | BASF SE (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20160157491-A1 | Pesticide Compounds | BASF SE (DE) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160157491-A1 | Pesticide Compounds | C1R, C1S, CBR3 | KDM4E 3731/4885ALDH1A1 2336/4885NPC1 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.