Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865294 | 1.00 | ATM (0.34) | ATMALDH1A1ACELMNAREN | |
| Hydrochloric Acid SCHEMBL25332117 | 0.98 | ATM (0.33) | ATMALDH1A1ACELMNAREN | |
| SCHEMBL13865296 | 0.81 | EPHX1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL1101660 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL4072231 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL29108935 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL24354973 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL13164365 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL10330907 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL18065044 | 0.78 | ATM (0.42) | ATMALDH1A1ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004086-A1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195230-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-12-11 | — | — | WO | disclosed |