Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401070 | 1.00 | ATM (0.34) | ATMALDH1A1ACELMNAREN | |
| Hydrochloric Acid SCHEMBL25332117 | 0.98 | ATM (0.33) | ATMALDH1A1ACELMNAREN | |
| SCHEMBL13865296 | 0.81 | EPHX1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL1101660 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL4072231 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL29108935 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL24354973 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL13164365 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL10330907 | 0.80 | ATM (0.44) | ATMALDH1A1ACE | |
| SCHEMBL18065044 | 0.78 | ATM (0.42) | ATMALDH1A1ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | ATM 2339/4885ALDH1A1 1789/4885ACE 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.