Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30663902 | 0.82 | MAPK1 (0.39) | PDE2AMAPK1TSHRALDH1A1TAAR1 | |
| SCHEMBL17732298 | 0.78 | PDE2A (0.51) | PDE2AMAPK1TSHRKMT2ANPSR1 | |
| SCHEMBL13711141 | 0.78 | PDE2A (0.46) | PDE2AALDH1A1 | |
| SCHEMBL27691584 | 0.78 | PDE2A (0.42) | PDE2A | |
| SCHEMBL13525385 | 0.77 | PDE2A (0.41) | PDE2AMAPK1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL28654444 | 0.76 | NPSR1 (0.36) | PDE2AMAPK1TSHRALDH1A1TAAR1 | |
| SCHEMBL20484507 | 0.76 | NPSR1 (0.36) | PDE2AMAPK1TSHRALDH1A1TAAR1 | |
| SCHEMBL28271533 | 0.76 | NPSR1 (0.36) | PDE2AMAPK1TSHRALDH1A1TAAR1 | |
| SCHEMBL29014067 | 0.76 | NPSR1 (0.36) | PDE2AMAPK1TSHRALDH1A1TAAR1 | |
| SCHEMBL13634476 | 0.75 | ALDH1A1 (0.36) | PDE2AMAPK1ALDH1A1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |
| CN-1934094-A | Diaryl substituted heterocyclic 5-membered ring derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| CN-1241195-A | Functionalized polymers | INFINEUM HOLDINGS B V (NL) | 2000-01-12 | — | — | CN | disclosed |