SCHEMBL1640177

SCHEMBL1640177

C[PH](C)(C)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2601909 0.71
SCHEMBL25218427 0.71 FFAR3 (0.42)
SCHEMBL1181781 0.67 FFAR3 (0.44)
Propionic Acid SCHEMBL27419361 0.67 FFAR3 (0.77)
SCHEMBL6538194 0.65 ALDH1A1 (0.36)
Propionic Acid SCHEMBL11426664 0.65
Glycine SCHEMBL28458918 0.64 GLRA1 (0.71)
SCHEMBL4371359 0.64
Bicarbonate SCHEMBL1065469 0.62
Propionic Acid SCHEMBL1331605 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192929-A1 COMPOSITIONS COMPRISING MULTIPLE CHARGED CATIONIC COMPOUNDS FOR SOIL RELEASE ECOLAB USA INC. 2023-06-22 US disclosed
US-20230183607-A1 SYNERGISTIC SURFACTANT PACKAGE FOR CLEANING OF FOOD AND OILY SOILS ECOLAB USA INC. 2023-06-15 US disclosed
CN-106061483-B Sustained release conjugates of SN-38 普洛林克斯有限责任公司 2021-01-08 CN disclosed
EP-3052101-B1 SLOW-RELEASE CONJUGATES OF SN-38 PROLYNX LLC (US) 2019-11-20 EP disclosed
US-10342792-B2 Slow-release conjugates of SN-38 PROLYNX LLC (US) 2019-07-09 US disclosed
EP-3277682-B1 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS DAIICHI SANKYO CO LTD (JP) 2019-04-24 EP disclosed
US-10174035-B2 6-morpholinyl-2-pyrazolyl-9H-purine derivatives and their use as PI3K inhibitors DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-01-08 US disclosed
US-20180289695-A1 SLOW-RELEASE CONJUGATES OF SN-38 PROLYNX LLC (US) 2018-10-11 US disclosed
US-10016411-B2 Slow-release conjugates of SN-38 PROLYNX LLC (US) 2018-07-10 US disclosed
US-20180072732-A1 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-03-15 US disclosed
WO-2007016650-A2 M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2007-02-08 WO disclosed
US-20020160270-A1 Compositions suitable for the use in electrochromic windows BRONSTERT BERND (DE) 2002-10-31 US disclosed
US-6335409-B1 LIQUID CRYSTAL ORIENTATION ROLIC AG (CH) 2002-01-01 US disclosed
US-6107427-A Cross-linkable, photoactive polymer materials ROLIC AG (CH) 2000-08-22 US disclosed
US-5234917-A Hypotensive agent, treatment of renal failure or glaucoma SMITHKLINE BEECHAM CORPORATION 1993-08-10 US disclosed
US-5114945-A Spiropiperidine derivatives GLAXO GROUP LIMITED (GB) 1992-05-19 US disclosed
EP-0330461-A2 Piperidine derivatives GLAXO GROUP LIMITED (GB) 1989-08-30 EP disclosed
EP-0107618-B1 N-SUBSTITUTED-2-(1-IMIDAZOLYL)-INDOLES CIBA-GEIGY AG (CH) 1986-07-16 EP disclosed
US-4539410-A THROMBOXANE SYNEHETASE INHIBITORS CIBA-GEIGY CORPORATION (US) 1985-09-03 US disclosed
EP-0107618-A1 N-substituted-2-(1-imidazolyl)-indoles CIBA-GEIGY AG (CH) 1984-05-02 EP disclosed