Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36888 | 0.96 | LMNA (0.54) | TSHRLMNAF2TDP1ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL28253326 | 0.96 | LMNA (0.54) | TSHRLMNAF2TDP1ALDH1A1 | |
| Bromide SCHEMBL26122064 | 0.94 | LMNA (0.52) | TSHRLMNAF2TDP1ALDH1A1 | |
| SCHEMBL28276150 | 0.94 | LMNA (0.52) | TSHRLMNAF2TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11176721 | 0.94 | LMNA (0.52) | TSHRLMNAF2TDP1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27546326 | 0.94 | LMNA (0.52) | TSHRLMNAF2TDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28091072 | 0.94 | LMNA (0.52) | TSHRLMNAF2TDP1ALDH1A1 | |
| Trimethylammonium SCHEMBL28659603 | 0.92 | TSHR (0.48) | TSHRLMNAF2TDP1ALDH1A1 | |
| Boric Acid SCHEMBL28807988 | 0.90 | LMNA (0.48) | TSHRLMNAF2TDP1ALDH1A1 | |
| Tetrylammonium SCHEMBL10763651 | 0.86 | LMNA (0.45) | TSHRLMNAF2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022206-B1 | EPHA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | UNIV HONG KONG SCIENCE & TECH (HK) | 2023-07-12 | — | — | EP | disclosed |
| US-9629830-B2 | EphA4 inhibitors as neuroprotective agents | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-04-25 | — | — | US | disclosed |
| US-20160152618-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-02 | — | — | US | disclosed |
| EP-3022206-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | The Hong Kong University of Science and Technology (CN) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015007222-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152618-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | EPHA4, EPHA1, EPHA7 | TSHR 3744/4885LMNA 3601/4885F2 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.