Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXN | P10599 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706723 | 0.71 | NPC1 (0.49) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL576058 | 0.64 | TXN (0.49) | TXNKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3022267 | 0.63 | KMT2A (0.51) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL22782149 | 0.63 | NPC1 (0.54) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL3703843 | 0.63 | NPC1 (0.51) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL575893 | 0.62 | HPGD (0.48) | TXNKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5729337 | 0.62 | KMT2A (0.43) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL22882906 | 0.62 | EHMT2 (0.55) | TXNKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5729334 | 0.62 | NPC1 (0.46) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL29601254 | 0.62 | EHMT2 (0.55) | TXNKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129811-B2 | Methods and compositions to prevent or treat bacterial infections | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-09-28 | — | — | US | claimed |
| US-10398682-B2 | Methods and compositions to prevent or treat bacterial infections | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-09-03 | — | — | US | claimed |
| US-20160151333-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-06-02 | — | — | US | claimed |
| US-11129811-B2 | Methods and compositions to prevent or treat bacterial infections | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-09-28 | — | — | US | disclosed |
| US-10478485-B2 | Methods and compositions to prevent or treat bacterial infections | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-11-19 | — | — | US | disclosed |
| US-10398682-B2 | Methods and compositions to prevent or treat bacterial infections | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180193442-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-07-12 | — | — | US | disclosed |
| WO-2017004545-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | KETTER PATRICK (US) | 2017-01-05 | — | — | WO | disclosed |
| US-20160151333-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-06-02 | — | — | US | disclosed |
| WO-2015009699-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | KETTER PATRICK (US) | 2015-01-22 | — | — | WO | disclosed |