SCHEMBL16402045

SCHEMBL16402045

Cc1cc(N2C=CC(C)(C)C=C2)n(C)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18011935 0.66 GRM4 (0.35) —
SCHEMBL18025885 0.65 — —
SCHEMBL16395731 0.63 PKM (0.42) SMN1; SMN2
SCHEMBL19720484 0.63 HSD17B10 (0.41) SMN1; SMN2
SCHEMBL16487535 0.61 SMN1; SMN2 (0.42) SMN1; SMN2
SCHEMBL23773506 0.59 HSD17B10 (0.48) SMN1; SMN2
SCHEMBL25069910 0.58 — —
SCHEMBL12495413 0.57 — —
SCHEMBL20049511 0.57 — —
SCHEMBL294386 0.57 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022180-B1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2022-02-23 — — EP disclosed
EP-3022180-B1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2022-02-23 — — EP disclosed
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2018-06-07 — — US disclosed
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2018-06-07 — — US disclosed
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2018-06-07 — — US disclosed
US-9920009-B2 UV absorbing compounds, compositions comprising same and uses thereof CORAL SUNSCREEN PTY LTD (AU) 2018-03-20 — — US disclosed
US-9920009-B2 UV absorbing compounds, compositions comprising same and uses thereof CORAL SUNSCREEN PTY LTD (AU) 2018-03-20 — — US disclosed
US-9920009-B2 UV absorbing compounds, compositions comprising same and uses thereof CORAL SUNSCREEN PTY LTD (AU) 2018-03-20 — — US disclosed
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2016-08-25 — — US disclosed
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2016-08-25 — — US disclosed
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof CORAL SUNSCREEN PTY LTD (AU) 2016-08-25 — — US disclosed
EP-3022180-A1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF Coral Sunscreen Pty Ltd (AU) 2016-05-25 — — EP disclosed
WO-2015006803-A1 UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF CORAL SUNSCREEN PTY LTD (AU) 2015-01-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155288-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof ERCC1, ERCC4, ERCC5 SMN1; SMN2 4094/4885
US-20160244409-A1 UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof ERCC4, ERCC1, ERCC5 SMN1; SMN2 4236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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