Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402558 | 0.89 | EZH2 (0.52) | EZH2 | |
| SCHEMBL17891403 | 0.89 | EZH2 (0.52) | EZH2 | |
| SCHEMBL16398387 | 0.84 | EZH2 (0.54) | EZH2 | |
| SCHEMBL17891365 | 0.84 | EZH2 (0.54) | EZH2 | |
| SCHEMBL16402619 | 0.82 | EZH2 (0.53) | EZH2 | |
| SCHEMBL16398141 | 0.82 | EZH2 (0.41) | EZH2 | |
| SCHEMBL16398072 | 0.82 | EZH2 (0.54) | EZH2 | |
| SCHEMBL17891382 | 0.82 | EZH2 (0.54) | EZH2 | |
| SCHEMBL16402549 | 0.81 | EZH2 (0.71) | EZH2 | |
| SCHEMBL16402552 | 0.81 | EZH2 (0.71) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015010049-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2015-01-22 | — | — | WO | disclosed |