Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 14/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15819727 | 0.84 | EZH2 (0.44) | EZH2 | |
| SCHEMBL15819725 | 0.84 | EZH2 (0.44) | EZH2 | |
| SCHEMBL16398094 | 0.84 | OPRM1 (0.50) | — | |
| SCHEMBL16402706 | 0.82 | EZH2 (0.49) | EZH2 | |
| SCHEMBL16397888 | 0.79 | EZH2 (0.40) | EZH2 | |
| SCHEMBL17891341 | 0.79 | EZH2 (0.45) | EZH2 | |
| SCHEMBL15819328 | 0.79 | EZH2 (0.43) | EZH2 | |
| SCHEMBL15819327 | 0.79 | EZH2 (0.43) | EZH2 | |
| SCHEMBL16398375 | 0.78 | OPRM1 (0.49) | — | |
| SCHEMBL16397502 | 0.78 | EZH2 (0.45) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015010049-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2015-01-22 | — | — | WO | disclosed |