Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403965 | 0.89 | BLM (0.52) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16403955 | 0.87 | NPC1 (0.51) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14315440 | 0.87 | BLM (0.51) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14325736 | 0.87 | BLM (0.58) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14315443 | 0.85 | RAB9A (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16403948 | 0.84 | TP53 (0.49) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16403953 | 0.83 | NPC1 (0.47) | BLMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14325735 | 0.83 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16403949 | 0.82 | NPC1 (0.49) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL16403950 | 0.81 | RAB9A (0.52) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |