Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.54 |
| ▸ | ATP4B | P51164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | PTPRF | P10586 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404136 | 0.89 | ATP4A (0.57) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL16404005 | 0.87 | ATP4A (0.59) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224920 | 0.86 | ATP4A (0.60) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224923 | 0.85 | ATP4A (0.59) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL16404003 | 0.85 | ATP4A (0.61) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224968 | 0.85 | ATP4A (0.59) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224939 | 0.84 | ATP4A (0.61) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224940 | 0.84 | ATP4A (0.56) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224943 | 0.84 | ATP4A (0.56) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL14224938 | 0.83 | CDC25A (0.53) | ATP4AATP4BALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |