Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.56 |
| ▸ | ATP4B | P51164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224939 | 0.88 | ATP4A (0.61) | ATP4AATP4BPOLBMAPK1MAPK10 | |
| SCHEMBL14224947 | 0.88 | MAPK1 (0.59) | ATP4AATP4BMAPK1MAPK10EIF4E | |
| SCHEMBL16404108 | 0.88 | ATP4A (0.56) | ATP4AATP4BMAPK1MAPK10EIF4E | |
| SCHEMBL14224966 | 0.88 | ATP4A (0.56) | ATP4AATP4BMAPK1MAPK10EIF4E | |
| SCHEMBL14315466 | 0.88 | ATP4A (0.58) | ATP4AATP4BMAPK1MAPK10EIF4E | |
| SCHEMBL16404008 | 0.87 | ATP4A (0.60) | ATP4AATP4BMAPK1MAPK10EIF4E | |
| SCHEMBL14224937 | 0.85 | ATP4A (0.53) | ATP4AATP4BMAPK1EIF4EALDH1A1 | |
| SCHEMBL14315465 | 0.84 | ATP4A (0.52) | ATP4AATP4BPOLBMAPK1MAPK10 | |
| SCHEMBL14224911 | 0.84 | ATP4A (0.56) | ATP4AATP4BPOLBMAPK1ALDH1A1 | |
| SCHEMBL16404009 | 0.84 | ATP4A (0.54) | ATP4AATP4BPOLBMAPK1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |