Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 18/20 | 0.53 |
| ▸ | AR | P10275 | 18/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12923951 | 0.88 | PGR (0.65) | PGRARNR3C2 | |
| SCHEMBL16404187 | 0.87 | PGR (0.57) | PGRARNR3C2 | |
| SCHEMBL12923970 | 0.86 | AR (0.56) | PGRARNR3C2 | |
| SCHEMBL13013594 | 0.83 | AR (0.53) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL16404171 | 0.83 | PGR (0.60) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL12906894 | 0.81 | PGR (0.37) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL16404175 | 0.81 | PGR (0.78) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL16404177 | 0.79 | AR (0.78) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL16404178 | 0.79 | PGR (0.80) | PGRARPDK1PDK2PDK3 | |
| SCHEMBL16404174 | 0.78 | AR (0.78) | PGRARPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937058-B2 | 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivative, use thereof, and medicament containing the derivative | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-20 | — | — | US | disclosed |