Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Everninate SCHEMBL31233848 | 1.00 | CYP3A4 (1.00) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL17779160 | 0.85 | CYP3A4 (0.74) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| Orsellinic Acid, Ethyl Ester SCHEMBL1648471 | 0.84 | CYP3A4 (1.00) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL950536 | 0.84 | CYP3A4 (1.00) | CYP3A4HPGDTDP1SMN1; SMN2KMT2A | |
| SCHEMBL10362928 | 0.83 | HPGD (0.71) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL4106403 | 0.83 | CYP3A4 (0.71) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL2580855 | 0.83 | CYP3A4 (0.70) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL12587021 | 0.81 | CYP3A4 (0.68) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL12770781 | 0.81 | CYP3A4 (0.68) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 | |
| SCHEMBL12552740 | 0.81 | CYP3A4 (0.74) | CYP3A4HPGDTDP1SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114994123-B | Method and device for testing thermal stability of substance | 江苏中烟工业有限责任公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-114994123-A | Method and device for testing thermal stability of substance | 江苏中烟工业有限责任公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-106397207-B | Tree ketonic acid A structural analogue, composition thereof and application thereof in medicines | 贵州医科大学 | 2020-12-08 | — | — | CN | disclosed |
| CN-110563690-A | Tree ketonic acid A structural analogue, composition thereof and application thereof in medicines | 贵州医科大学 | 2019-12-13 | — | — | CN | disclosed |
| US-9890351-B2 | Encapsulates | THE PROCTER & GAMBLE COMPANY (US) | 2018-02-13 | — | — | US | disclosed |
| EP-2741731-B1 | ENCAPSULATES | PROCTER & GAMBLE (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-2308861-B1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | EISAI R&D MAN CO LTD (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-8889614-B2 | Encapsulates | THE PROCTER & GAMBLE COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| EP-2468239-B1 | Encapsulates | PROCTER & GAMBLE INTERNAT OPERATIONS SA (CH) | 2013-09-18 | — | — | EP | disclosed |
| US-20130196987-A1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | EISAI CO., LTD. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-7572805-B2 | Pyrrolo(oxo)isoquinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1778225-A2 | PYRROLO(OXO)ISOQUINOLINES AS 5HT LIGANDS | Bristol-Myers Squibb Company (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| WO-2006019886-A2 | PYRROLO(OXO)ISOQUINOLINES AS 5HT LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060014777-A1 | Pyrrolo(oxo)isoquinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY | 2006-01-19 | — | — | US | disclosed |
| US-6900340-B2 | Preparation of isocoumarin derivatives and intermediates for the synthesis thereof | MERCIAN CORPORATION (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040102639-A1 | Preparation of isocoumarin derivatives and intermediates for the synthesis thereof | MERCIAN CORPORATION (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1364947-A1 | PREPARATION OF ISOCOUMARIN DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Mercian Corporation (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196987-A1 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS | FLT4, VEGFA, FLT1 | CYP3A4 1158/4885HPGD 333/4885TDP1 3097/4885 |
| US-20040102639-A1 | Preparation of isocoumarin derivatives and intermediates for the synthesis thereof | IDH1, IDH3A, IDH2 | CYP3A4 73/4885HPGD 76/4885TDP1 4756/4885 |
| US-20060014777-A1 | Pyrrolo(oxo)isoquinolines as 5HT ligands | HTR2B, OPRD1, HTR1B | CYP3A4 1738/4885HPGD 2536/4885TDP1 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.