Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.70 |
| ▸ | CNR1 | P21554 | 7/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961519 | 0.85 | CNR2 (0.74) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL16404242 | 0.82 | CNR2 (1.00) | CNR2CNR1FAAH | |
| SCHEMBL16404199 | 0.73 | CNR2 (0.57) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL16404243 | 0.72 | CNR2 (1.00) | CNR2CNR1FAAHALDH1A1HPGD | |
| SCHEMBL16404231 | 0.71 | CNR2 (0.65) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL30634268 | 0.71 | FAAH (0.61) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL2638097 | 0.71 | NPC1 (0.56) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL4963283 | 0.69 | CNR2 (0.62) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL3687439 | 0.69 | CNR2 (1.00) | CNR2CNR1FAAHALDH1A1HPGD | |
| SCHEMBL16404201 | 0.69 | CNR2 (0.65) | CNR2CNR1FAAHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |