Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.67 |
| ▸ | CNR2 | P34972 | 9/20 | 0.67 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404246 | 0.87 | CNR1 (0.61) | CNR1CNR2MDM2CYP1A2CYP3A4 | |
| SCHEMBL16404257 | 0.86 | CNR1 (0.60) | CNR1CNR2GRM5KDM4EALDH1A1 | |
| SCHEMBL16404212 | 0.86 | CNR2 (0.66) | CNR1CNR2MDM2CYP1A2CYP3A4 | |
| SCHEMBL16404241 | 0.85 | CNR1 (0.61) | CNR1CNR2MDM2GRM5CYP1A2 | |
| SCHEMBL16404206 | 0.84 | CNR1 (0.60) | CNR1CNR2GRM5 | |
| SCHEMBL5999099 | 0.83 | CNR1 (0.65) | CNR1CNR2GRM5NPC1RAB9A | |
| SCHEMBL16404252 | 0.82 | CNR1 (0.57) | CNR1CNR2GRM5 | |
| SCHEMBL2033217 | 0.81 | CNR1 (0.65) | CNR1CNR2GRM5RAB9AALDH1A1 | |
| SCHEMBL16404232 | 0.79 | CNR2 (0.56) | CNR1CNR2MDM2CYP1A2CYP3A4 | |
| SCHEMBL16404230 | 0.79 | CNR2 (0.66) | CNR1CNR2MDM2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |