Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404204 | 0.85 | CNR1 (0.67) | CNR1CNR2MDM2CYP1A2CYP3A4 | |
| SCHEMBL16404246 | 0.82 | CNR1 (0.61) | CNR1CNR2MDM2CYP1A2CYP3A4 | |
| SCHEMBL16404257 | 0.75 | CNR1 (0.60) | CNR1CNR2NPY5RKDM4EKMT2A | |
| SCHEMBL16404232 | 0.74 | CNR2 (0.56) | CNR1CNR2NPY5RMDM2CYP1A2 | |
| SCHEMBL16404230 | 0.74 | CNR2 (0.66) | CNR1CNR2NPY5RMDM2CYP1A2 | |
| SCHEMBL16404212 | 0.74 | CNR2 (0.66) | CNR1CNR2NPY5RMDM2CYP1A2 | |
| SCHEMBL16404222 | 0.72 | CNR2 (0.74) | CNR1CNR2 | |
| SCHEMBL16404251 | 0.72 | CNR1 (0.61) | CNR1CNR2NPY5RGRM5 | |
| SCHEMBL16404206 | 0.70 | CNR1 (0.60) | CNR1CNR2GRM5 | |
| SCHEMBL5999099 | 0.69 | CNR1 (0.65) | CNR1CNR2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |