Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.65 |
| ▸ | CNR1 | P21554 | 12/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404255 | 0.82 | CNR1 (0.70) | CNR2CNR1KMT2A | |
| SCHEMBL4509587 | 0.80 | CNR1 (0.75) | CNR2CNR1 | |
| SCHEMBL6702070 | 0.80 | CNR1 (0.89) | CNR2CNR1 | |
| SCHEMBL3687436 | 0.79 | CNR2 (1.00) | CNR2CNR1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16404253 | 0.79 | CNR1 (0.57) | CNR2CNR1HTT | |
| SCHEMBL16404210 | 0.78 | CNR2 (0.72) | CNR2CNR1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6699879 | 0.77 | CNR1 (0.77) | CNR2CNR1 | |
| SCHEMBL6700636 | 0.77 | CNR1 (0.81) | CNR2CNR1 | |
| SCHEMBL2033217 | 0.76 | CNR1 (0.65) | CNR2CNR1TP53RAB9AHPGD | |
| SCHEMBL16404261 | 0.75 | CNR1 (0.60) | CNR2CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |