Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.70 |
| ▸ | CNR2 | P34972 | 8/20 | 0.70 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 9/20 | 0.48 |
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173492 | 0.87 | CNR2 (0.54) | CNR1CNR2RIPK1KMT2A | |
| SCHEMBL16404223 | 0.82 | CNR2 (0.65) | CNR1CNR2KMT2A | |
| SCHEMBL16404434 | 0.78 | CNR2 (0.70) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404245 | 0.76 | CNR2 (0.60) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404211 | 0.76 | CNR1 (0.68) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404239 | 0.76 | CNR2 (0.60) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404253 | 0.76 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL14269469 | 0.76 | RIPK1 (0.48) | CNR1CNR2RIPK1KMT2A | |
| SCHEMBL14173508 | 0.76 | RIPK1 (0.48) | CNR1CNR2RIPK1KMT2A | |
| SCHEMBL6613583 | 0.75 | PLK1 (0.61) | CNR1CNR2RIPK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |