Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 7/20 | 0.51 |
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404253 | 0.80 | CNR1 (0.57) | CNR1CNR2HTT | |
| SCHEMBL3684239 | 0.79 | CNR1 (0.57) | ALDH1A1TSHRCNR1CNR2MAPT | |
| SCHEMBL23889217 | 0.77 | CNR1 (0.56) | ALDH1A1CNR1CNR2MAPK1HSD17B10 | |
| SCHEMBL1078089 | 0.77 | CNR1 (0.56) | ALDH1A1TSHRCNR1CNR2MAPT | |
| SCHEMBL16063426 | 0.76 | CNR1 (0.54) | ALDH1A1TSHRCNR1CNR2HPGD | |
| SCHEMBL5783509 | 0.76 | POLB (0.52) | ALDH1A1TSHRCNR1CNR2MAPT | |
| Lithium Ion SCHEMBL1078086 | 0.75 | CNR2 (0.56) | TSHRCNR1CNR2MAPK1HSD17B10 | |
| SCHEMBL31372 | 0.75 | HPGD (0.80) | ALDH1A1TSHRHPGDHSD17B10KMT2A | |
| Adamantane SCHEMBL27759633 | 0.74 | CNR2 (0.70) | ALDH1A1TSHRCNR1CNR2HSD17B10 | |
| SCHEMBL16404223 | 0.74 | CNR2 (0.65) | ALDH1A1CNR1CNR2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |