SCHEMBL16404229

SCHEMBL16404229

Cc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)n1-c1ccc(F)cc1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.79
CNR1 P21554 6/20 0.79
GRM5 P41594 8/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404250 0.89 CNR2 (0.79) CNR2CNR1GRM5
SCHEMBL3687439 0.88 CNR2 (1.00) CNR2CNR1
SCHEMBL16404260 0.81 CNR2 (0.67) CNR2CNR1
SCHEMBL16404217 0.80 CNR2 (0.75) CNR2CNR1GRM5
SCHEMBL4963336 0.78 CNR2 (0.80) CNR2CNR1
SCHEMBL16404220 0.77 CNR2 (1.00) CNR2CNR1
SCHEMBL16404244 0.77 CNR2 (1.00) CNR2CNR1
SCHEMBL16404222 0.77 CNR2 (0.74) CNR2CNR1
SCHEMBL16404236 0.76 CNR2 (1.00) CNR2CNR1
SCHEMBL16404213 0.76 CNR2 (1.00) CNR2CNR1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937184-B2 1H-imidazole derivatives as cannabinoid CB2 receptor modulators ABBVIE B.V. (NL) 2015-01-20 US disclosed
US-8937184-B2 1H-imidazole derivatives as cannabinoid CB2 receptor modulators ABBVIE B.V. (NL) 2015-01-20 US disclosed