Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.78 |
| ▸ | CNR1 | P21554 | 11/20 | 0.78 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687436 | 0.88 | CNR2 (1.00) | CNR2CNR1HSD11B1LMNAHPGD | |
| SCHEMBL16404193 | 0.80 | CNR2 (1.00) | CNR2CNR1HPGDALDH1A1 | |
| SCHEMBL16404256 | 0.79 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL16404210 | 0.75 | CNR2 (0.72) | CNR2CNR1LMNAHPGDALDH1A1 | |
| SCHEMBL16404225 | 0.74 | CNR2 (0.56) | CNR2CNR1LMNA | |
| Adamantane SCHEMBL27759633 | 0.73 | CNR2 (0.70) | CNR2CNR1ALDH1A1 | |
| SCHEMBL16404247 | 0.73 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL5998360 | 0.73 | CNR2 (0.63) | CNR2CNR1HSD11B1LMNAHPGD | |
| SCHEMBL16404195 | 0.72 | CNR2 (0.84) | CNR2CNR1HPGDALDH1A1 | |
| SCHEMBL16404212 | 0.71 | CNR2 (0.66) | CNR2CNR1LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |