Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.57 |
| ▸ | CNR2 | P34972 | 8/20 | 0.57 |
| ▸ | GRM5 | P41594 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404261 | 0.82 | CNR1 (0.60) | CNR1CNR2GRM5HTR2AHTR2C | |
| SCHEMBL2033217 | 0.78 | CNR1 (0.65) | CNR1CNR2GRM5 | |
| SCHEMBL20647071 | 0.77 | CNR1 (0.54) | CNR1CNR2GRM5 | |
| SCHEMBL4961512 | 0.77 | CNR1 (0.55) | CNR1CNR2GRM5 | |
| SCHEMBL16063426 | 0.77 | CNR1 (0.54) | CNR1CNR2GRM5 | |
| SCHEMBL3684239 | 0.77 | CNR1 (0.57) | CNR1CNR2GRM5 | |
| SCHEMBL16404211 | 0.75 | CNR1 (0.68) | CNR1CNR2GRM5HTR2AHTR2C | |
| SCHEMBL23889217 | 0.75 | CNR1 (0.56) | CNR1CNR2GRM5 | |
| SCHEMBL1078089 | 0.75 | CNR1 (0.56) | CNR1CNR2GRM5 | |
| SCHEMBL16404248 | 0.74 | CNR1 (0.60) | CNR1CNR2GRM5HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |