Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.60 |
| ▸ | CNR2 | P34972 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404207 | 0.92 | GRM5 (0.57) | CNR1CNR2ALDH1A1GRM5 | |
| SCHEMBL3684239 | 0.77 | CNR1 (0.57) | CNR1CNR2ALDH1A1GRM5HTT | |
| SCHEMBL23889217 | 0.75 | CNR1 (0.56) | CNR1CNR2ALDH1A1GRM5HTT | |
| SCHEMBL4961512 | 0.75 | CNR1 (0.55) | CNR1CNR2ALDH1A1GRM5POLB | |
| SCHEMBL16063426 | 0.74 | CNR1 (0.54) | CNR1CNR2ALDH1A1GRM5HTT | |
| SCHEMBL30387595 | 0.73 | WNT3A (0.61) | CNR1CNR2GRM5 | |
| SCHEMBL20604171 | 0.73 | WNT3A (0.61) | CNR1CNR2GRM5 | |
| Lithium Ion SCHEMBL1078086 | 0.73 | CNR2 (0.56) | CNR1CNR2GRM5HTTMAPK1 | |
| SCHEMBL16404239 | 0.73 | CNR2 (0.60) | CNR1CNR2HTR2AHTR2CSLC6A4 | |
| SCHEMBL16404211 | 0.73 | CNR1 (0.68) | CNR1CNR2GRM5HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |