Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | PDE9A | O76083 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850810 | 0.93 | OPRM1 (0.70) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL16905355 | 0.89 | OPRM1 (0.65) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL7858207 | 0.88 | BCHE (0.72) | OPRM1BCHECNR2CNR1TRPV1 | |
| SCHEMBL7849313 | 0.83 | OPRM1 (0.79) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL19198164 | 0.82 | OPRM1 (0.70) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL7857365 | 0.81 | OPRM1 (0.86) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL17299108 | 0.81 | OPRM1 (0.86) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL19472315 | 0.81 | OPRM1 (0.86) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL20201994 | 0.81 | OPRM1 (0.69) | OPRM1ACE2BCHECNR2CNR1 | |
| SCHEMBL19198725 | 0.81 | OPRM1 (0.69) | OPRM1ACE2BCHECNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176208-B1 | PRODRUGS OF CANNABIDIOL, COMPOSITIONS COMPRISING PRODRUGS OF CANNABIDIOL AND METHODS OF USING THE SAME | ZYNERBA PHARMACEUTICALS INC (US) | 2015-01-21 | — | — | EP | disclosed |