Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP10 | Q14694 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641854 | 0.93 | KDM4E (0.53) | PTGER4PTGDRMAPTKDM4EALDH1A1 | |
| SCHEMBL1640540 | 0.93 | KDM4E (0.53) | PTGER4PTGDRMAPTKDM4EALDH1A1 | |
| SCHEMBL1641721 | 0.93 | KDM4E (0.53) | PTGER4PTGDRMAPTKDM4EALDH1A1 | |
| SCHEMBL1641827 | 0.85 | BRD4 (0.57) | MAPTP2RX3MEN1KMT2A | |
| SCHEMBL1640573 | 0.79 | BRD4 (0.65) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL1640357 | 0.77 | EGLN3 (0.66) | PTGER4PTGDRUSP10MEN1KMT2A | |
| SCHEMBL1642053 | 0.76 | MAPT (0.59) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL1640326 | 0.76 | HSP90AA1 (0.58) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL1642389 | 0.75 | EGLN1 (0.48) | ALDH1A1 | |
| SCHEMBL1640352 | 0.75 | LMNA (0.55) | MAPTKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | PTGER4 1880/4885PTGDR 899/4885MAPT 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.