Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112040 | 0.97 | — | — | |
| Fluoride SCHEMBL28877073 | 0.93 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| Hydrochloric Acid SCHEMBL10426264 | 0.93 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| Chloroform SCHEMBL9943936 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL11025387 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| SCHEMBL11762263 | 0.83 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| SCHEMBL251582 | 0.81 | — | — | |
| Formaldoxime SCHEMBL29083081 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL4154603 | 0.81 | ALDH1A1 (0.95) | ALDH1A1CYP1A2CYP2A6TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL28157846 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2A6TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | ALDH1A1 227/4885CYP1A2 361/4885CYP2A6 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.