SCHEMBL16407237

SCHEMBL16407237

O=C1c2cc3ccccc3cc2C(=O)c2cc3cc(Br)ccc3cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.64
PTPRC P08575 1/20 0.53
S100A4 P26447 1/20 0.50
BCL2 P10415 3/20 0.47
MCL1 Q07820 2/20 0.47
CYP1A2 P05177 3/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GSTP1 P09211 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.39
CDC25B P30305 1/20 0.39
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17859354 0.98 CYP2A6 (0.61) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL1304448 0.94 PTPRC (0.62) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL15210982 0.94 S100A4 (0.56) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL15210826 0.94 S100A4 (0.56) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL29649816 0.94 S100A4 (0.56) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL12877800 0.88 PTPRC (0.70) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL19922655 0.86 PTPRC (0.68) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL17836984 0.86 PTPRC (0.68) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL31195893 0.86 PTPRC (0.68) CYP2A6PTPRCS100A4BCL2MCL1
SCHEMBL11959834 0.84 PTPRC (0.51) CYP2A6PTPRCS100A4BCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062080-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2018-03-01 US disclosed
US-9799830-B2 Organic semiconductor compositions SMARTKEM LIMITED (GB) 2017-10-24 US disclosed
US-9799830-B2 Organic semiconductor compositions SMARTKEM LIMITED (GB) 2017-10-24 US disclosed
US-20150034878-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-02-05 US disclosed
US-20150034878-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-02-05 US disclosed
US-20150028261-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-01-29 US disclosed
US-20150028261-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-01-29 US disclosed
US-20150021524-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-01-22 US disclosed