Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.63 |
| ▸ | CNR2 | P34972 | 11/20 | 0.63 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | BRD1 | O95696 | 1/20 | 0.52 |
| ▸ | CCL2 | P13500 | 1/20 | 0.52 |
| ▸ | TAF1 | P21675 | 1/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641067 | 0.99 | CNR1 (0.65) | CNR1CNR2BRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL1642259 | 0.88 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL1642081 | 0.86 | ALDH1A1 (0.53) | CNR1CNR2ALDH1A1NPC1MAPT | |
| SCHEMBL1642163 | 0.85 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL1642256 | 0.81 | MEN1 (0.49) | CNR1CNR2ALDH1A1NPC1MAPT | |
| SCHEMBL1640573 | 0.80 | BRD4 (0.65) | BRD4ALDH1A1SMN1; SMN2MAPTTRIM24 | |
| SCHEMBL1641827 | 0.80 | BRD4 (0.57) | BRD4MAPTBRD2BRD3BRDT | |
| SCHEMBL1641226 | 0.80 | BRD4 (0.53) | CNR1CNR2BRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL1640326 | 0.79 | HSP90AA1 (0.58) | CNR2BRD4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1642053 | 0.79 | MAPT (0.59) | BRD4ALDH1A1SMN1; SMN2MAPTBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | CNR1 2636/4885CNR2 2738/4885BRD4 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.