Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16408979 | 1.00 | DRD3 (0.48) | DRD3DRD2KMT2ANPC1ALDH1A1 | |
| SCHEMBL3782375 | 0.80 | NOTUM (0.50) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL16408968 | 0.80 | NOTUM (0.50) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL3782373 | 0.80 | NOTUM (0.50) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL16408948 | 0.80 | NOTUM (0.50) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL3780250 | 0.80 | KDM4E (0.47) | DRD3DRD2ALDH1A1HTR1AHTR2A | |
| SCHEMBL3780247 | 0.80 | KDM4E (0.47) | DRD3DRD2ALDH1A1HTR1AHTR2A | |
| SCHEMBL3282297 | 0.76 | ESR1 (0.49) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL3282323 | 0.76 | ESR1 (0.49) | DRD3DRD2HTR1AHTR2AHRH1 | |
| SCHEMBL31121204 | 0.76 | ESR1 (0.49) | DRD3DRD2HTR1AHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007897-A1 | METHOD OF RACEMISATION OF UNDESIRED ENANTIOMERS | LEK PHARMACEUTICALS D.D. (SI) | 2015-01-22 | — | — | WO | disclosed |