SCHEMBL16409378

SCHEMBL16409378

C=CC(=O)OC(C)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.34
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193167 0.85
SCHEMBL15836525 0.82 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10457339 0.81 HCAR2 (0.38)
SCHEMBL2283715 0.81
SCHEMBL7718060 0.81 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5457746 0.81
SCHEMBL3182391 0.80 TSHR (0.30) TSHR
SCHEMBL12783788 0.80 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28358779 0.78 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8451861 0.78 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112695525-B Flame-retardant waterproof oil-proof finishing agent and preparation method thereof 京准化工技术(上海)有限公司 2023-06-16 CN disclosed
CN-112695525-A Flame-retardant waterproof and oil-proof finishing agent and preparation method thereof 京准化工技术(上海)有限公司 2021-04-23 CN disclosed
US-9842993-B2 Film-forming composition, film formed thereby, and method for manufacturing organic semiconductor element using same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-12-12 US disclosed
US-20160181531-A1 Film-Forming Composition, Film Formed Thereby, and Method for Manufacturing Organic Semiconductor Element Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2016-06-23 US disclosed
WO-2015008720-A1 FILM-FORMING COMPOSITION, FILM FORMED THEREBY, AND METHOD FOR MANUFACTURING ORGANIC SEMICONDUCTOR ELEMENT USING SAME セントラル硝子株式会社 (JP) 2015-01-22 WO disclosed