SCHEMBL28358779

SCHEMBL28358779

C=CC(=O)OC(F)(F)C(C)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.32
ALDH1A1 P00352 4/20 0.31
TP53 P04637 3/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15157338 0.86
SCHEMBL8451861 0.83 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9548406 0.83 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL42233 0.83 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL786625 0.82 ALDH1A1 (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21819966 0.82 ALDH1A1 (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL63733 0.79 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6432837 0.79
SCHEMBL221408 0.78 ALDH1A1 (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL786417 0.78 ALDH1A1 (0.33) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592051-A Water-based wear-resistant polyurethane resin for basalt fiber pultrusion and preparation method and application thereof 北京玄泽新材料科技有限公司 2025-03-11 CN claimed
CN-117264462-A Coating containing modified fluorosilane composite sol and preparation method thereof 广东美涂士建材股份有限公司 2023-12-22 CN claimed
CN-112898855-A extremely-low-VOC (volatile organic compound) water-based green environment-friendly wood coating and preparation method thereof 常州乐丽得新材料有限公司 2021-06-04 CN claimed
CN-112898854-A Universal water-based LED photocureable plastic coating and preparation method thereof 常州乐丽得新材料有限公司 2021-06-04 CN claimed
CN-110845678-A Fluorine modified silica sol/polystyrene-acrylate nano core-shell emulsion and preparation method and application thereof 佛山市新量子环保材料有限公司 2020-02-28 CN claimed
CN-110746839-A Fluorine-acrylic acid modified phosphoric acid resin water-based paint and preparation method and application thereof 佛山市新量子环保材料有限公司 2020-02-04 CN claimed
CN-119592051-A Water-based wear-resistant polyurethane resin for basalt fiber pultrusion and preparation method and application thereof 北京玄泽新材料科技有限公司 2025-03-11 CN disclosed
CN-117264462-A Coating containing modified fluorosilane composite sol and preparation method thereof 广东美涂士建材股份有限公司 2023-12-22 CN disclosed
CN-112898855-A extremely-low-VOC (volatile organic compound) water-based green environment-friendly wood coating and preparation method thereof 常州乐丽得新材料有限公司 2021-06-04 CN disclosed
CN-112898854-A Universal water-based LED photocureable plastic coating and preparation method thereof 常州乐丽得新材料有限公司 2021-06-04 CN disclosed
CN-110845678-A Fluorine modified silica sol/polystyrene-acrylate nano core-shell emulsion and preparation method and application thereof 佛山市新量子环保材料有限公司 2020-02-28 CN disclosed
CN-110746839-A Fluorine-acrylic acid modified phosphoric acid resin water-based paint and preparation method and application thereof 佛山市新量子环保材料有限公司 2020-02-04 CN disclosed