Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.48 |
| ▸ | NPY1R | P25929 | 7/20 | 0.48 |
| ▸ | NPY2R | P49146 | 5/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TFPI | P10646 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343536 | 0.92 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL31343396 | 0.92 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL17955405 | 0.92 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL30395232 | 0.90 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31410685 | 0.90 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL31211745 | 0.90 | FOLH1 (0.45) | NPY4RNPY1RNPY2RNPY5ROPRL1 | |
| SCHEMBL31691755 | 0.89 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RTLR2 | |
| SCHEMBL30254242 | 0.89 | GNAI3 (0.43) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL19629051 | 0.88 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL19614687 | 0.88 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014197763-A1 | MOLECULAR DESIGN TOWARD DUAL-MODALITY PROBES FOR RADIOISOTOPE-BASED IMAGING (PET OR SPECT) AND MRI | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEAS SYSTEM (US) | 2014-12-11 | — | — | WO | disclosed |