Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972563 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1616084 | 0.87 | — | — | |
| SCHEMBL16588379 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| Fluoride SCHEMBL11245451 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| Fluoride SCHEMBL11250158 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL22911174 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1314968 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1314964 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| Methane SCHEMBL10746573 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8679860 | 0.79 | HRH3 (0.50) | KDM4EALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123991-A1 | TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN | POSEIDON INNOVATION 1, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| EP-3145929-B1 | 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-01-13 | — | — | EP | disclosed |
| WO-2014197313-A2 | NOVEL COMPOUNDS AND USES THEREOF | KALA PHARMACEUTICALS, INC. (US) | 2014-12-11 | — | — | WO | disclosed |