SCHEMBL16409669

SCHEMBL16409669

N=Cc1ccc2c(c1)CCc1c-2noc1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
S1PR1 P21453 17/20 0.43
IP6K1 Q92551 1/20 0.41
IP6K3 Q96PC2 1/20 0.41
IP6K2 Q9UHH9 1/20 0.41
S1PR3 Q99500 10/20 0.37
CYP3A4 P08684 1/20 0.35
CYP2C8 P10632 1/20 0.35
KCNH2 Q12809 1/20 0.35
TRPV1 Q8NER1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401663 0.90 IP6K1 (0.43) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16401240 0.90 S1PR1 (0.44) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16400700 0.87 CYP1A2 (0.45) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL19315816 0.83 S1PR1 (0.38) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16400173 0.82 CYP1A2 (0.48) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16400797 0.82 CYP1A2 (0.48) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL19315819 0.79 S1PR1 (0.36) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16409670 0.78 S1PR1 (0.36) CYP1A2CYP2D6S1PR1IP6K1IP6K3
SCHEMBL16400772 0.78 CYP1A2 (0.51) CYP1A2CYP2D6S1PR1S1PR3CYP3A4
SCHEMBL16401572 0.76 LMNA (0.44) S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP disclosed
WO-2015007682-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2015-01-22 WO disclosed