Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 15/20 | 0.35 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12151575 | 1.00 | ALDH1A1 (0.38) | ALDH1A1ABCB1SLC43A1 | |
| SCHEMBL12300838 | 0.90 | ALDH1A1 (0.38) | ALDH1A1ABCB1 | |
| SCHEMBL12330324 | 0.90 | ALDH1A1 (0.38) | ALDH1A1ABCB1 | |
| SCHEMBL13530762 | 0.90 | ALDH1A1 (0.38) | ALDH1A1ABCB1 | |
| SCHEMBL29324933 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ABCB1SLC43A1 | |
| SCHEMBL6972453 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ABCB1SLC43A1 | |
| SCHEMBL13530760 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12151574 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16409753 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12300849 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139604-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150025039-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025039-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | TYMP, ITPA, PNP | ALDH1A1 4754/4885ABCB1 3217/4885SLC43A1 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.