Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278744 | 0.85 | CA12 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11282436 | 0.80 | CYSLTR2 (0.44) | — | |
| SCHEMBL9820774 | 0.78 | MCHR1 (0.49) | HDAC6 | |
| SCHEMBL10064553 | 0.76 | MCHR1 (0.48) | — | |
| SCHEMBL6150497 | 0.76 | HDAC1 (0.52) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11858914 | 0.75 | HTR1D (0.46) | — | |
| SCHEMBL16409784 | 0.74 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL16409780 | 0.73 | HDAC1 (0.70) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1137647 | 0.73 | CA12 (0.43) | — | |
| SCHEMBL11267353 | 0.72 | POLB (0.40) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014196328-A1 | HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 日本理化学工業株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |