Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16409778 | 0.85 | HDAC1 (0.53) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11282436 | 0.84 | CYSLTR2 (0.44) | MMP1MMP9MMP12CNR2PDE3B | |
| SCHEMBL9820774 | 0.82 | MCHR1 (0.49) | CA12CA9HDAC6MEN1NR1I2 | |
| SCHEMBL10064553 | 0.80 | MCHR1 (0.48) | CA12CA9DRD2MMP1MMP9 | |
| SCHEMBL11267353 | 0.76 | POLB (0.40) | CA12CA9DRD2DRD4DRD3 | |
| SCHEMBL11858914 | 0.76 | HTR1D (0.46) | CA12CA9DRD2DRD4DRD3 | |
| SCHEMBL11272663 | 0.74 | PDE3B (0.44) | CA12CA9HDAC6MMP1KCNH2 | |
| SCHEMBL11287477 | 0.74 | MCL1 (0.43) | LMNAALBBCL2MCL1PDE3B | |
| SCHEMBL1137647 | 0.74 | CA12 (0.43) | CA12CA9MEN1LMNAMAPT | |
| SCHEMBL6849540 | 0.74 | HTR1B (0.63) | CNR2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |