SCHEMBL16409922

SCHEMBL16409922

c1ccc(N(c2ccccc2)c2ccc(-c3cc(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)cc(-c4ccc(-n5c6ccccc6c6c7sc8ccccc8c7ccc65)cc4)c3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 3/20 0.32
PIK3CD O00329 1/20 0.30
BRD4 O60885 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
KCNH2 Q12809 1/20 0.30
BRDT Q58F21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16409934 0.98 ALOX5 (0.34) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL16409923 0.93 ALOX5 (0.34) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL10108547 0.92 PRKDC (0.35) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL10108649 0.91 ALOX5 (0.35) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL17126167 0.91 PRKDC (0.35) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL17126165 0.91 PRKDC (0.35) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL15804131 0.91 ALOX5 (0.39) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL10108538 0.90 PRKDC (0.35) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL15759589 0.90 ALOX5 (0.40) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL16283059 0.89 ALOX5 (0.41) ALOX5PRKDCPIK3CDBRD4PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014196805-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-12-11 WO disclosed