Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410633 | 0.80 | ACAT2 (0.37) | KMT2AAKT2 | |
| SCHEMBL16410737 | 0.74 | ACAT2 (0.35) | KMT2AAKT2 | |
| SCHEMBL16410601 | 0.73 | — | — | |
| SCHEMBL16410561 | 0.73 | TSHR (0.39) | KMT2AKCNQ2 | |
| SCHEMBL16410657 | 0.73 | ACAT2 (0.33) | KMT2A | |
| SCHEMBL16410670 | 0.73 | — | — | |
| SCHEMBL16410703 | 0.72 | AKT2 (0.33) | AKT2 | |
| SCHEMBL16410612 | 0.71 | ACAT2 (0.33) | — | |
| SCHEMBL16410840 | 0.71 | ACAT2 (0.42) | KMT2A | |
| SCHEMBL16410817 | 0.70 | ACAT2 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |