Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410737 | 0.91 | ACAT2 (0.35) | — | |
| SCHEMBL16410691 | 0.84 | CXCR4 (0.30) | — | |
| SCHEMBL16410538 | 0.80 | KMT2A (0.32) | — | |
| SCHEMBL16410633 | 0.80 | ACAT2 (0.37) | — | |
| SCHEMBL16410689 | 0.79 | EPHX2 (0.32) | — | |
| SCHEMBL16410634 | 0.78 | CXCR4 (0.34) | — | |
| SCHEMBL16410730 | 0.78 | ACAT2 (0.39) | — | |
| SCHEMBL17757802 | 0.75 | ACAT2 (0.43) | — | |
| SCHEMBL16410754 | 0.75 | KMT2A (0.37) | — | |
| SCHEMBL16410601 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |