Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | ACAT2 | Q9BWD1 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410809 | 0.90 | ACAT2 (0.35) | ACAT2TAAR1 | |
| SCHEMBL16410791 | 0.90 | ACAT2 (0.33) | ACAT2TAAR1 | |
| SCHEMBL17757585 | 0.89 | PDE7A (0.36) | PDE7AACAT2TAAR1KDM4EMAPT | |
| SCHEMBL16410747 | 0.87 | PDE7A (0.38) | PDE7AACAT2MAPTKMT2A | |
| SCHEMBL16410824 | 0.87 | PDE7A (0.38) | PDE7AACAT2MAPTKMT2A | |
| SCHEMBL16410623 | 0.86 | SSTR3 (0.36) | PDE7AACAT2KMT2A | |
| SCHEMBL17757594 | 0.84 | PDE7A (0.38) | PDE7AACAT2TAAR1KDM4EMAPT | |
| SCHEMBL16410765 | 0.84 | ACAT2 (0.47) | ACAT2TAAR1KDM4EMAPTKMT2A | |
| SCHEMBL16410834 | 0.83 | ACAT2 (0.36) | ACAT2TAAR1KDM4EMAPTKMT2A | |
| SCHEMBL16410745 | 0.83 | TAAR1 (0.35) | ACAT2TAAR1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |