Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410795 | 0.82 | — | — | |
| SCHEMBL16410627 | 0.77 | SLC6A2 (0.33) | — | |
| SCHEMBL17757229 | 0.76 | PIK3CA (0.40) | ACAT2 | |
| SCHEMBL16410745 | 0.76 | TAAR1 (0.35) | ACAT2 | |
| SCHEMBL16410827 | 0.76 | — | — | |
| SCHEMBL17757524 | 0.75 | SLC6A4 (0.36) | ACAT2 | |
| SCHEMBL16410800 | 0.75 | BRD4 (0.35) | — | |
| SCHEMBL16410791 | 0.74 | ACAT2 (0.33) | ACAT2 | |
| SCHEMBL16410616 | 0.74 | ACAT2 (0.39) | ACAT2 | |
| SCHEMBL16410824 | 0.73 | PDE7A (0.38) | ACAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |