Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410682 | 0.77 | HDAC1 (0.39) | P2RX7 | |
| SCHEMBL16410829 | 0.72 | ACAT2 (0.39) | — | |
| SCHEMBL16410665 | 0.71 | ACAT2 (0.31) | — | |
| SCHEMBL16410725 | 0.71 | KDM4E (0.40) | — | |
| SCHEMBL16410586 | 0.71 | MYC (0.31) | — | |
| SCHEMBL16410860 | 0.70 | PIK3CA (0.33) | — | |
| SCHEMBL16410687 | 0.69 | ACAT2 (0.34) | — | |
| SCHEMBL16410840 | 0.68 | ACAT2 (0.42) | CHRM2 | |
| SCHEMBL16410782 | 0.67 | ACAT2 (0.34) | CHRM2 | |
| SCHEMBL16410858 | 0.67 | PIK3CA (0.35) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |