Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410767 | 0.87 | ACAT2 (0.43) | ACAT2ROCK2 | |
| SCHEMBL16410630 | 0.84 | ACAT2 (0.38) | ACAT2 | |
| SCHEMBL16410863 | 0.83 | ACAT2 (0.35) | ACAT2ROCK2 | |
| SCHEMBL16410728 | 0.81 | ACAT2 (0.42) | ACAT2 | |
| SCHEMBL16410789 | 0.79 | ACAT2 (0.38) | ACAT2ROCK2 | |
| SCHEMBL17757056 | 0.79 | PIK3CA (0.39) | ACAT2 | |
| SCHEMBL16410766 | 0.79 | ACAT2 (0.47) | ACAT2 | |
| SCHEMBL16410787 | 0.78 | ACAT2 (0.33) | ACAT2 | |
| SCHEMBL16410694 | 0.78 | ACAT2 (0.47) | ACAT2 | |
| SCHEMBL16410680 | 0.77 | ACAT2 (0.37) | ACAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |