Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.58 |
| ▸ | HTR2A | P28223 | 20/20 | 0.58 |
| ▸ | DRD3 | P35462 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505630 | 1.00 | DRD2 (0.58) | DRD2HTR2ADRD3 | |
| SCHEMBL321986 | 0.88 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL10161622 | 0.88 | DRD2 (0.52) | DRD2HTR2ADRD3 | |
| SCHEMBL12505634 | 0.88 | DRD2 (0.52) | DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL322307 | 0.87 | DRD2 (0.51) | DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL321674 | 0.87 | DRD2 (0.51) | DRD2HTR2ADRD3 | |
| SCHEMBL15911353 | 0.86 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL14874309 | 0.86 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL1394592 | 0.85 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL321757 | 0.85 | DRD2 (0.76) | DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590984-B1 | ANELLATED PYRIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2015-01-28 | — | — | EP | claimed |