SCHEMBL16414552

SCHEMBL16414552

OCCCCc1ccc2cc(Cl)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 3/20 0.49
ALOX15 P16050 3/20 0.49
CYP2A6 P11509 1/20 0.42
CYP1A2 P05177 1/20 0.41
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
P2RY12 Q9H244 1/20 0.40
CA2 P00918 2/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
BCHE P06276 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
AKR1B1 P15121 1/20 0.39
TBXA2R P21731 1/20 0.38
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16413995 0.98 IGF1R (0.47) IGF1RALOX15CYP2A6CYP1A2PDE3B
SCHEMBL16414610 0.98 IGF1R (0.47) IGF1RALOX15CYP2A6CYP1A2PDE3B
SCHEMBL16414559 0.94 IGF1R (0.46) IGF1RALOX15CYP2A6CYP1A2PDE3B
SCHEMBL4948986 0.89 IGF1R (0.44) IGF1RALOX15CYP2A6CYP1A2PDE3B
SCHEMBL16414453 0.86 KDM4E (0.47) IGF1RALOX15CYP2A6CYP1A2CA2
SCHEMBL9670577 0.82 CYP1A2 (0.50) IGF1RALOX15CYP1A2PDE3BPDE3A
SCHEMBL15352127 0.81 IGF1R (0.44) IGF1RALOX15CYP2A6CYP1A2HDAC1
SCHEMBL15352327 0.81 IGF1R (0.44) IGF1RALOX15CYP2A6CYP1A2HDAC1
SCHEMBL130490 0.81 CYP1A2 (0.61) IGF1RALOX15CYP2A6CYP1A2HDAC1
SCHEMBL15351993 0.80 IGF1R (0.43) IGF1RALOX15CYP2A6CYP1A2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE CBR3, CYP51A1, CYP8B1 IGF1R 1383/4885ALOX15 1685/4885CYP2A6 127/4885
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES CBR3, CYCS, CBR1 IGF1R 877/4885ALOX15 1669/4885CYP2A6 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.